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Richard S E Keefe Selected Research

Perphenazine (Trilafon)

11/2009The effects of antipsychotic medications on emotion perception in patients with chronic schizophrenia in the CATIE trial.
10/2008Extrapyramidal side-effects of antipsychotics in a randomised trial.
5/2008What CATIE found: results from the schizophrenia trial.
4/2008Employment outcomes in a randomized trial of second-generation antipsychotics and perphenazine in the treatment of individuals with schizophrenia.
6/2007Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial.
3/2007Effectiveness of olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia after discontinuing perphenazine: a CATIE study.
12/2006Cost-effectiveness of second-generation antipsychotics and perphenazine in a randomized trial of treatment for chronic schizophrenia.
9/2005Effectiveness of antipsychotic drugs in patients with chronic schizophrenia.

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Richard S E Keefe Research Topics

Disease

78Schizophrenia (Dementia Praecox)
10/2021 - 01/2003
28Psychotic Disorders (Schizoaffective Disorder)
01/2022 - 09/2003
17Cognitive Dysfunction
01/2022 - 02/2008
5Tardive Dyskinesia
03/2011 - 12/2005
4Major Depressive Disorder (Major Depressive Disorders)
01/2018 - 05/2014
3Substance-Related Disorders (Drug Abuse)
12/2018 - 12/2005
3Neurobehavioral Manifestations
03/2016 - 07/2009
3Alzheimer Disease (Alzheimer's Disease)
12/2015 - 08/2011
3Headache (Headaches)
08/2015 - 11/2010
3Psychomotor Agitation (Akathisia)
12/2011 - 12/2005
2Bipolar Disorder (Manic Depressive Psychosis)
12/2017 - 11/2014
2Diarrhea
07/2015 - 11/2010
1Anhedonia
01/2020
1Mental Disorders (Mental Disorder)
01/2017
1Constipation
08/2015
1Nausea
07/2015
1Conduct Disorder (Conduct Disorders)
12/2011
1Movement Disorders (Movement Disorder)
12/2011
1Hallucinations (Hallucination)
11/2011
1Dystonia (Limb Dystonia)
10/2008
1Prodromal Symptoms
10/2008
1Parkinsonian Disorders (Parkinsonism)
10/2008
1Psychotic Affective Disorders
02/2008
1Eosinophilia
04/2006

Drug/Important Bio-Agent (IBA)

51Antipsychotic Agents (Antipsychotics)IBA
12/2018 - 01/2003
18Olanzapine (Zyprexa)FDA Link
08/2011 - 09/2003
16Risperidone (Risperdal Consta)FDA LinkGeneric
06/2014 - 09/2003
10Quetiapine Fumarate (Seroquel)FDA Link
08/2011 - 04/2006
8Perphenazine (Trilafon)FDA LinkGeneric
11/2009 - 09/2005
7ziprasidone (Geodon)FDA Link
04/2011 - 04/2006
6Cholinergic Antagonists (Anticholinergics)IBA
01/2021 - 12/2005
5Biological ProductsIBA
01/2021 - 02/2008
5Haloperidol (Haldol)FDA LinkGeneric
10/2006 - 09/2003
4Pharmaceutical PreparationsIBA
01/2021 - 11/2011
3Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
03/2016 - 05/2008
3Lurasidone HydrochlorideFDA Link
01/2016 - 02/2011
32- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
07/2014 - 12/2006
2BI 409306IBA
10/2021 - 01/2019
2VortioxetineIBA
01/2018 - 07/2015
2N- (7- chloro- N- quinuclidin- 3- yl)benzo(b)thiophene- 2- carboxamideIBA
12/2015 - 02/2015
2Clozapine (Clozaril)FDA LinkGeneric
08/2015 - 04/2006
2Indicators and Reagents (Reagents)IBA
09/2014 - 02/2011
2PregnenoloneIBA
09/2014 - 07/2009
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
09/2014 - 07/2009
2gamma-Aminobutyric Acid (GABA)IBA
09/2014 - 03/2011
2NeurosteroidsIBA
09/2014 - 07/2009
2Paliperidone PalmitateFDA Link
06/2014 - 11/2010
2Aripiprazole (Abilify)FDA Link
06/2014 - 05/2008
1Biomarkers (Surrogate Marker)IBA
10/2021
1Polytetrafluoroethylene (Teflon)FDA Link
10/2021
1Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2021
1Glycine Plasma Membrane Transport ProteinsIBA
01/2021
1BI 425809IBA
01/2021
1Opioid Receptors (Opioid Receptor)IBA
01/2020
1Opioid Analgesics (Opioids)IBA
01/2020
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
01/2019
1Dopamine (Intropin)FDA LinkGeneric
05/2018
1roluperidoneIBA
05/2018
1TabletsIBA
01/2017
1N- (2- (pyridin- 3- ylmethyl)- 1- azabicyclo(2.2.2)oct- 3- yl)- 1- benzofuran- 2- carboxamideIBA
03/2016
1Minocycline (Cyclops)FDA LinkGeneric
08/2015
1Capsules (Microcapsules)IBA
08/2015
1Duloxetine Hydrochloride (Cymbalta)FDA Link
07/2015
1Histamine (Histamine Dihydrochloride)FDA Link
05/2015
1GSK239512IBA
05/2015
1NicotineFDA Link
02/2015
1N- ((3S)- 1- azabicyclo(2.2.2)oct- 3- yl)- 1H- indazole- 3- carboxamide hydrochlorideIBA
06/2014
1Lisdexamfetamine DimesylateFDA Link
05/2014
1Antidepressive Agents (Antidepressants)IBA
05/2014
1Aligeron (AS 2)IBA
03/2014
1Oxygen (Dioxygen)IBA
12/2013
1Retinaldehyde (Retinal)IBA
12/2013
1Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
05/2013
1Complement System Proteins (Complement)IBA
05/2013
1Nootropic Agents (Nootropics)IBA
01/2013
1Adenosine (Adenocard)FDA LinkGeneric
06/2012
1Allopurinol (Remid)FDA LinkGeneric
06/2012
1Dopamine AntagonistsIBA
06/2012
1davunetideIBA
04/2012
1Peptides (Polypeptides)IBA
04/2012
1Aminobutyrates (Aminobutyric Acid)IBA
03/2011
17- (1,1- dimethylethyl)- 6- (2- ethyl- 2H- 1,2,4- triazol- 3- ylmethoxy)- 3- (2- fluorophenyl)- 1,2,4- triazolo(4,3- b)pyridazineIBA
03/2011
1GABA-A Receptors (GABA(A) Receptor)IBA
03/2011
1Modafinil (Provigil)FDA Link
11/2010
1Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
07/2010
1pregnenolone sulfateIBA
07/2009
1Neuregulin-1 (Neuregulin 1)IBA
10/2008
1Cholinesterase Inhibitors (Anticholinesterases)IBA
05/2008
1Donepezil (Aricept)FDA LinkGeneric
05/2008
1Cholinergic Agents (Cholinergics)IBA
05/2008
1GoldIBA
09/2007
1Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
04/2007

Therapy/Procedure

5Therapeutics
01/2022 - 11/2010
3Drug Therapy (Chemotherapy)
01/2021 - 08/2014
2Behavior Control
11/2014 - 09/2014
1Activities of Daily Living (ADL)
01/2020
1Cognitive Training
01/2019
1Polypharmacy
11/2011
1AT protocol
08/2011
1Aftercare (After-Treatment)
03/2008